How to evaluate almost 10 million people in Wuhan in 19 days? How to guarantee precision?

A few days ago, many people from Wuhan met and greeted: Did they have nucleic acid? Nearly 9.9 million residents and temporary residents of Wuhan have not undergone further coronavirus nucleic acid testing. Almost 9.9 million people have undergone nucleic acid testing. Along with those who have previously conducted tests, Wuhan has accumulated a total of 1,090.9 Tens of thousands of people have completed the nucleic acid tests and have basically covered all personnel. No confirmed cases were found. 300 asymptomatic infections were detected, with a detection rate of 0.303 per 10,000. So how is the detection of nearly 10 million people organized effectively and in an orderly fashion? So what does large-scale testing rely on to ensure accuracy? What does this result mean? What impact will it have on the next prevention and control of epidemics?

This is the site where residents of the Zhanggongdi community, Qiaokou District, Wuhan, performed nucleic acid tests. The location of the test was established in an open field and a semi-open space near the community. Residents queued for numbers, recorded information, and then received samples of pharyngeal swabs.

A week before the test, community network staff informed WeChat group residents of the arrangement for nucleic acid testing, and the time period for residents to be tested was defined in units of buildings to reduce waiting in line. There were volunteers and community workers at the test site.

To prevent cross infection and facilitate residents, concentrated nucleic acid detection in Wuhan City established sampling points in the community, primarily taking communities as organizational units, and sampling by community organizations at intervals. of time, giving priority to the detection of previously infected and old communities.

Faced with such a wide range of test population, the effectiveness of sampling is an important prerequisite for ensuring test accuracy. Before the start of the sampling, the professionals receive training in a unified way and, at the same time, they establish clear and unified standards. On site, the Wuhan City Health Planning and Family Law Enforcement Monitoring Team will also carry out on-site supervision.

Some residents missed the first round of sampling due to several reasons: to detect full coverage as much as possible, the city of Wuhan launched the second round of "vacancy verification and leak filling" in the district units.

There are also older people, people with disabilities, and other residents with limited mobility who did not participate in the previous test, and medical personnel also sampled on-site during this period.

From May 25 to June 1, Wuhan City established a total of 249 "leak acquisition and sampling points".

To guarantee the effectiveness of this nucleic acid test, on the one hand, the sampling must be as complete as possible, on the other hand, the detection of these samples must be precise. From May 14 to June 1, over a period of 19 days, compared to almost 9.9 million samples, to complete the test in a short period of time, many test institutions have increased investment in personnel and equipment.

In addition to the original 23 testing institutions, Wuhan has mobilized 40 medical institutions and disease control centers across the city. The number of third-party test institutions increased from 419 to 1,451, and the number of test teams increased from 215 to 701.

This time, the Wuhan Mingzhi Medical Testing Laboratory is one of the institutions that performs nucleic acid testing and, once the samples are collected and delivered every day, the testing staff will scan the code and receive them for the first time .

Staff strictly adhere to relevant operating procedures, process samples and test nucleic acid, and test results are obtained after approximately 4 to 5 hours. Through the change of personnel in the test organization, continuous equipment, and 24-hour full-load operation, Wuhan's daily test capacity quickly broke down from 300,000 to 1 million.

At the same time, in order to improve the efficiency of the test, in addition to the individual person, the single tube and the single sample, a quarter of the samples sampled were analyzed using the mixed detection method, and up to five samples were analyzed. mixed in a detection tube for detection. 

Once an abnormality is detected in the sample results, all individual samples in this mixed sample will be analyzed separately.

In order to improve efficiency while ensuring accuracy, new required sampling tests are also configured. A further 35,961 samples were taken from various test institutions to retest, and the results were in full agreement with the initial test results, indicating that the quality of the test was very reliable.

In the test results, the asymptomatic infected person is the special situation that appears in this new Covid19 outbreak, which is the focus of everyone's attention. The press conference on June 2 also detailed the relevant situation of asymptomatic infections: among the nearly 9.9 million people examined, only 300 were asymptomatic infections, and none of them became confirmed cases. 1174 of the close contacts had negative results in the nucleic acid test.

Although these 300 asymptomatic infected people have not become confirmed cases, to avoid potential risks to the greatest extent, the CDC of Wuhan conducted a sample of 300 families and living environments of asymptomatic infected people. A total of 3,343 samples of masks, glasses, toothbrushes, mobile phones and floors, furniture, door handles, toilets, floor drains, etc. were collected, and a total of 3,343 samples of elevator keys were collected, hallway elements etc.

For asymptomatic individuals, the Liaison Group of the Joint Prevention and Control Mechanism of the State Council also instructed Wuhan City to form a team of clinical experts and psychology experts to achieve "one person, one plan" for diagnosis and treatment of asymptomatic patients. Asymptomatic infected individuals should go to designated hospitals or community health service centers for follow-up and follow-up visits in the second and fourth weeks after the release of centralized medical observation for follow-up follow-up and treatment closed circuit.

In addition to centralized staff screening, on June 1, the Wuhan Center for Disease Control also collected samples of tap water, domestic sewage, taxis, buses, wagons and subway stations, shopping malls, restaurants, parks , etc. in Wuhan, and collected a total of 2,314 samples from some pets that were also negative.

Hu Yabo, a member of the Standing Committee of the Wuhan Municipal Committee and Executive Deputy Mayor of Wuhan City, said: "The cost of this centralized nucleic acid test is borne by the government, and the cost is reduced through centralized acquisition. The total expenditure is about 900 million yuan. This assessment has been changed for the national people rest assured the tranquility of the Wuhan people. On April 8, Wuhan achieved physical unlocking; after detection and investigation Centralized nucleic acids, the people of Wuhan who made great sacrifices during the closure of the city realized the psychological unlocking. "

With the announcement of the test results, more industries and departments in Wuhan have accelerated the pace of returning to normalization. Citizens who go to the hospital to go to the ordinary outpatient clinic will resume the previous process and will no longer need to perform new nucleic acid tests; community control measures for community residents will also be gradually relaxed; The school has also accelerated the rate of return to school, and some schools have begun eliminating emergency drills to prepare students to return to school. Wuhan University, Wuhan University of Technology, Huazhong University of Agriculture and other universities have successively issued back-to-school notices and graduates are expected to return to campus and take a real graduation photo.

Experts noted that Wuhan's centralized research maximized the number of bases to make citizens feel more comfortable, Wuhan is safer, and more importantly, through this centralized investigation, potential ones can be further eliminated hidden dangers and taking precise steps for the next step in preventing and controlling the Wuhan epidemic; this entered the bases.

At the same time, places where new cases can be found in hospitals, such as fever clinics, still need to be well verified to protect existing prevention and control outcomes.

Concentrating our efforts on the detection of nucleic acid of almost 10 million people represents the concept of "the people come first, life first", and it is also a powerful measure to prevent and control the epidemic. Through this comprehensive survey, based on the large data collected, the next normal epidemic prevention and control measures will be more scientific and accurate At the same time, it is also a node for Wuhan to further restore their vitality. On April 8, Wuhan achieved a physical unlock; this test to some extent enabled the people of Wuhan to achieve a psychological unlock, allowing Wuhan people leave their homes more calm and relaxed. Normal life and work. Of course, once again, the virus is very cunning and the risk of infection is also changing dynamically. Relaxing the mind does not mean relaxing the Surveillance - Attention should be paid and some precautions should be taken.

-Surging News